Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection.

Although Escherichia coli K1 strains are benign commensals in adults, their acquisition at birth by the newborn may result in life-threatening systemic infections, most commonly sepsis and meningitis. Key features of these infections, including stable gastrointestinal (GI) colonization and age-depen...

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Bibliographic Details
Main Authors: Alex J McCarthy, David Negus, Patricia Martin, Catarina Pechincha, Eric Oswald, Richard A Stabler, Peter W Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5115809?pdf=render