Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition
Ebola virus high lethality relies on its ability to efficiently bypass the host innate antiviral response, which senses the viral dsRNA through the RIG-I receptor and induces type I interferon α/β production. In the bypassing action, the Ebola virus protein VP35 plays a pivotal role at multiple leve...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2019-11-01
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| Series: | Antiviral Chemistry & Chemotherapy |
| Online Access: | https://doi.org/10.1177/2040206619889220 |