Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project.

BACKGROUND:Venous thromboembolism (VTE) is a common disease where known genetic risk factors explain only a small portion of the genetic variance. Then, the analysis of intermediate phenotypes, such as thrombin generation assay, can be used to identify novel genetic risk factors that contribute to V...

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Bibliographic Details
Main Authors: Laura Martin-Fernandez, Andrey Ziyatdinov, Marina Carrasco, Juan Antonio Millon, Angel Martinez-Perez, Noelia Vilalta, Helena Brunel, Montserrat Font, Anders Hamsten, Juan Carlos Souto, José Manuel Soria
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4718515?pdf=render