Topical Dexamethasone Administration Impairs Protein Synthesis and Neuronal Regeneration in the Olfactory Epithelium

Topical Dexamethasone Administration Impairs Protein Synthesis and Neuronal Regeneration in the Olfactory Epithelium

Chronic inflammatory process in the nasal mucosa is correlated with poor smell perception. Over-activation of immune cells in the olfactory epithelium (OE) is generally associated with loss of olfactory function, and topical steroidal anti-inflammatory drugs have been largely used for treating such...

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Bibliographic Details
Main Authors: Umberto Crisafulli, André M. Xavier, Fabiana B. dos Santos, Tavane D. Cambiaghi, Seo Y. Chang, Marimélia Porcionatto, Beatriz A. Castilho, Bettina Malnic, Isaias Glezer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
anosmia
inflammation
corticoids
innate immune response
neurogenesis
neuronal cell death
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00050/full

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http://journal.frontiersin.org/article/10.3389/fnmol.2018.00050/full

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