The LRR-TM protein PAN-1 interacts with MYRF to promote its nuclear translocation in synaptic remodeling

The LRR-TM protein PAN-1 interacts with MYRF to promote its nuclear translocation in synaptic remodeling

Neural circuits develop through a plastic phase orchestrated by genetic programs and environmental signals. We have identified a leucine-rich-repeat domain transmembrane protein PAN-1 as a factor required for synaptic rewiring in C. elegans. PAN-1 localizes on cell membrane and binds with MYRF, a me...

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Bibliographic Details
Main Authors: Shi-Li Xia, Meng Li, Bing Chen, Chao Wang, Yong-Hong Yan, Meng-Qiu Dong, Yingchuan B Qi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
synaptic rewiring
laval development
MYRF
pan-1
membrane-bound
transcription factors
Online Access:https://elifesciences.org/articles/67628

Internet

https://elifesciences.org/articles/67628

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