Cortical dynein pulling mechanism is regulated by differentially targeted attachment molecule Num1

Cortical dynein pulling mechanism is regulated by differentially targeted attachment molecule Num1

Cortical dynein generates pulling forces via microtubule (MT) end capture-shrinkage and lateral MT sliding mechanisms. In Saccharomyces cerevisiae, the dynein attachment molecule Num1 interacts with endoplasmic reticulum (ER) and mitochondria to facilitate spindle positioning across the mother-bud n...

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Bibliographic Details
Main Authors: Safia Omer, Samuel R Greenberg, Wei-Lih Lee
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
nuclear migration
spindle positioning
dynein
yeast
dynactin
Online Access:https://elifesciences.org/articles/36745

Internet

https://elifesciences.org/articles/36745

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