Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration

Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration

How salamanders accomplish progenitor cell proliferation while faithfully maintaining genomic integrity and regenerative potential remains elusive. Here we found an innate DNA damage response mechanism that is evident during blastema proliferation (early- to late-bud) and studied its role during tis...

Full description

Bibliographic Details
Main Authors: Konstantinos Sousounis, Donald M Bryant, Jose Martinez Fernandez, Samuel S Eddy, Stephanie L Tsai, Gregory C Gundberg, Jihee Han, Katharine Courtemanche, Michael Levin, Jessica L Whited
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
axolotl
regeneration
progenitor cells
DNA damage response
limb regeneration
Online Access:https://elifesciences.org/articles/51217

Internet

https://elifesciences.org/articles/51217

Similar Items