Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses.

Mechanical Strain Causes Adaptive Change in Bronchial Fibroblasts Enhancing Profibrotic and Inflammatory Responses.

Asthma is characterized by periodic episodes of bronchoconstriction and reversible airway obstruction; these symptoms are attributable to a number of factors including increased mass and reactivity of bronchial smooth muscle and extracellular matrix (ECM) in asthmatic airways. Literature has suggest...

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Bibliographic Details
Main Authors: Wiparat Manuyakorn, David E Smart, Antonio Noto, Fabio Bucchieri, Hans Michael Haitchi, Stephen T Holgate, Peter H Howarth, Donna E Davies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4839664?pdf=render

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http://europepmc.org/articles/PMC4839664?pdf=render

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