Genetic compatibility and virulence of reassortants derived from contemporary avian H5N1 and human H3N2 influenza A viruses.

The segmented structure of the influenza virus genome plays a pivotal role in its adaptation to new hosts and the emergence of pandemics. Despite concerns about the pandemic threat posed by highly pathogenic avian influenza H5N1 viruses, little is known about the biological properties of H5N1 viruse...

Full description

Bibliographic Details
Main Authors: Li-Mei Chen, C Todd Davis, Hong Zhou, Nancy J Cox, Ruben O Donis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2374906?pdf=render