Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling

Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling

Endothelial cells respond to molecular and physical forces in development and vascular homeostasis. Deregulation of endothelial responses to flow-induced shear is believed to contribute to many aspects of cardiovascular diseases including atherosclerosis. However, how molecular signals and shear-med...

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Bibliographic Details
Main Authors: Claudio A Franco, Martin L Jones, Miguel O Bernabeu, Anne-Clemence Vion, Pedro Barbacena, Jieqing Fan, Thomas Mathivet, Catarina G Fonseca, Anan Ragab, Terry P Yamaguchi, Peter V Coveney, Richard A Lang, Holger Gerhardt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-02-01
Series:eLife
Subjects:
angiogenesis
retinal vasculature
vessel regression
shear stress
flow sensing
Online Access:https://elifesciences.org/articles/07727

Internet

https://elifesciences.org/articles/07727

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