Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence

Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence

Clostridium difficile is a spore-forming anaerobic bacterium that causes colitis in patients with disrupted colonic microbiota. While some individuals are asymptomatic C. difficile carriers, symptomatic disease ranges from mild diarrhea to potentially lethal toxic megacolon. The wide disease spectru...

Full description

Bibliographic Details
Main Authors: Brittany B. Lewis, Rebecca A. Carter, Lilan Ling, Ingrid Leiner, Ying Taur, Mini Kamboj, Erik R. Dubberke, Joao Xavier, Eric G. Pamer, Jimmy D. Ballard
Format: Article
Language:English
Published: American Society for Microbiology 2017-08-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/4/e00885-17

Internet

http://mbio.asm.org/cgi/content/full/8/4/e00885-17

Similar Items