The Significance of MicroRNAs Expression in Regulation of Extracellular Matrix and Other Drug Resistant Genes in Drug Resistant Ovarian Cancer Cell Lines

The Significance of MicroRNAs Expression in Regulation of Extracellular Matrix and Other Drug Resistant Genes in Drug Resistant Ovarian Cancer Cell Lines

Ovarian cancer rates the highest mortality among all gynecological malignancies. The main reason for high mortality is the development of drug resistance. It can be related to increased expression of drug transporters and increased expression of extracellular matrix (ECM) proteins. Our foremost aim...

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Bibliographic Details
Main Authors: Dominika Kazmierczak, Karol Jopek, Karolina Sterzynska, Barbara Ginter-Matuszewska, Michal Nowicki, Marcin Rucinski, Radoslaw Januchowski
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
microRNA
ATP-binding cassette subfamily B member 1 gene (<i>ABCB1</i>)
collagen type III alpha 1 chain gene (<i>COL3A1</i>)
ovarian cancer
drug resistance
Online Access:https://www.mdpi.com/1422-0067/21/7/2619

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https://www.mdpi.com/1422-0067/21/7/2619

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