MiR-21 enhances melanoma invasiveness via inhibition of tissue inhibitor of metalloproteinases 3 expression: in vivo effects of MiR-21 inhibitor.

Metastatic melanoma is the most aggressive form of this cancer. It is important to understand factors that increase or decrease metastatic activity in order to more effectively research and implement treatments for melanoma. Increased cell invasion through the extracellular matrix is required for me...

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Main Authors: Sara E Martin del Campo, Nicholas Latchana, Kala M Levine, Valerie P Grignol, Ene T Fairchild, Alena Cristina Jaime-Ramirez, Thao-Vi Dao, Volodymyr I Karpa, Mary Carson, Akaansha Ganju, Anthony N Chan, William E Carson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4294659?pdf=render