Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies
The ability to detect and/or manipulate specific cell populations based upon the presence of intracellular protein epitopes would enable many types of studies and applications. Protein binders such as nanobodies (Nbs) can target untagged proteins (antigens) in the intracellular environment. However,...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/15312 |