Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies

The ability to detect and/or manipulate specific cell populations based upon the presence of intracellular protein epitopes would enable many types of studies and applications. Protein binders such as nanobodies (Nbs) can target untagged proteins (antigens) in the intracellular environment. However,...

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Bibliographic Details
Main Authors: Jonathan CY Tang, Eugene Drokhlyansky, Behzad Etemad, Stephanie Rudolph, Binggege Guo, Sui Wang, Emily G Ellis, Jonathan Z Li, Constance L Cepko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
GFP
Online Access:https://elifesciences.org/articles/15312