PremPDI estimates and interprets the effects of missense mutations on protein-DNA interactions.

PremPDI estimates and interprets the effects of missense mutations on protein-DNA interactions.

Protein-DNA interactions play important roles in regulations of many vital cellular processes, including transcription, translation, DNA replication and recombination. Sequence variants occurring in these DNA binding proteins that alter protein-DNA interactions may cause significant perturbations or...

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Bibliographic Details
Main Authors: Ning Zhang, Yuting Chen, Feiyang Zhao, Qing Yang, Franco L Simonetti, Minghui Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006615

Internet

https://doi.org/10.1371/journal.pcbi.1006615

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