PremPDI estimates and interprets the effects of missense mutations on protein-DNA interactions.
Protein-DNA interactions play important roles in regulations of many vital cellular processes, including transcription, translation, DNA replication and recombination. Sequence variants occurring in these DNA binding proteins that alter protein-DNA interactions may cause significant perturbations or...
Main Authors: | Ning Zhang, Yuting Chen, Feiyang Zhao, Qing Yang, Franco L Simonetti, Minghui Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-12-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1006615 |
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