Resveratrol inhibits Cdk5 activity through regulation of p35 expression

<p>Abstract</p> <p>Background</p> <p>We have previously reported that cyclin-dependent kinase 5 (Cdk5) participates in the regulation of nociceptive signaling. Through activation of the ERK1/2 pathway, Tumor Necrosis Factor-α (TNF-α) induces expression of Egr-1. This re...

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Bibliographic Details
Main Authors: Kulkarni Ashok B, Iadarola Michael J, Keller Jason, Terse Anita, Utreras Elias
Format: Article
Language:English
Published: SAGE Publishing 2011-07-01
Series:Molecular Pain
Subjects:
Online Access:http://www.molecularpain.com/content/7/1/49