Pioglitazone improves fat distribution, the adipokine profile and hepatic insulin sensitivity in non-diabetic end-stage renal disease subjects on maintenance dialysis: a randomized cross-over pilot study.

Pioglitazone improves fat distribution, the adipokine profile and hepatic insulin sensitivity in non-diabetic end-stage renal disease subjects on maintenance dialysis: a randomized cross-over pilot study.

Fat redistribution, increased inflammation and insulin resistance are prevalent in non-diabetic subjects treated with maintenance dialysis. The aim of this study was to test whether pioglitazone, a powerful insulin sensitizer, alters body fat distribution and adipokine secretion in these subjects an...

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Bibliographic Details
Main Authors: Anne Zanchi, Luc Tappy, Kim-Anne Lê, Murielle Bortolotti, Nicolas Theumann, Georges Halabi, Thierry Gauthier, Claudine Mathieu, Sylvie Tremblay, Pauline Coti Bertrand, Michel Burnier, Daniel Teta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4199598?pdf=render

Internet

http://europepmc.org/articles/PMC4199598?pdf=render

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