Chronic Lymphocytic Leukemia Cells Are Activated and Proliferate in Response to Specific T Helper Cells

There is increasing interest in the chronic lymphocytic leukemia (CLL) microenvironment and the mechanisms that may promote CLL cell survival and proliferation. A role for T helper (Th) cells has been suggested, but current evidence is only circumstantial. Here we show that CLL patients had memory...

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Bibliographic Details
Main Authors: Audun Os, Simone Bürgler, Anna Parente Ribes, Ane Funderud, Dong Wang, Keith M. Thompson, Geir E. Tjønnfjord, Bjarne Bogen, Ludvig A. Munthe
Format: Article
Language:English
Published: Elsevier 2013-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713003586