Phase 1 trial of preoperative image guided intensity modulated proton radiation therapy with simultaneously integrated boost to the high risk margin for retroperitoneal sarcomas

Purpose: To conduct phase 1 and 2 trials with photon intensity modulated radiation therapy and intensity modulated proton therapy (IMPT) arms to selectively escalate the retroperitoneal sarcoma preoperative radiation dose to tumor volume (clinical target volume [CTV] 2) that is judged to be at a hig...

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Main Authors: Thomas F. DeLaney, MD, Yen-Lin Chen, MD, Elizabeth H. Baldini, MD MPH, Dian Wang, MD PhD, Judith Adams, CMD, Shea B. Hickey, BA, Beow Y. Yeap, ScD, Stephen M. Hahn, MD, Karen De Amorim Bernstein, MD, G. Petur Nielsen, MD, Edwin Choy, MD PhD, John T. Mullen, MD, Sam S. Yoon, MD
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109416300689