A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers.

A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers.

BACKGROUND AND AIMS: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV infection in Asian populations. Most significant ass...

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Bibliographic Details
Main Authors: Johannes Vermehren, Jörn Lötsch, Simone Susser, Sabine Wicker, Annemarie Berger, Stefan Zeuzem, Christoph Sarrazin, Alexandra Doehring
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3308944?pdf=render

Internet

http://europepmc.org/articles/PMC3308944?pdf=render

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