A protective role for complement C3 protein during pandemic 2009 H1N1 and H5N1 influenza A virus infection.

Highly pathogenic H5N1 influenza infections are associated with enhanced inflammatory and cytokine responses, severe lung damage, and an overall dysregulation of innate immunity. C3, a member of the complement system of serum proteins, is a major component of the innate immune and inflammatory respo...

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Bibliographic Details
Main Authors: Kevin B O'Brien, Thomas E Morrison, David Y Dundore, Mark T Heise, Stacey Schultz-Cherry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3052313?pdf=render