High glucose burden inhibits EGFR/PI3K/AKT1/mTOR signaling pathway in cutaneous fibroblasts

Diabetic healing failure is the clinical expression of countless molecular and cellular disorders having hyperglycemia as the proximal trigger. The fibroblast is a critical building-block cell type for the healing process. Under high glucose concentrations fibroblasts physiology is perturbed. The ep...

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Bibliographic Details
Main Authors: Yssel Mendoza-Marí, Ariana Garcia-Ojalvo, Maday Fernández-Mayola, Luis Herrera-Martínez, Jorge Berlanga-Acosta
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522014000400003&lng=en&tlng=en