Butorphanol Promotes Macrophage Phenotypic Transition to Inhibit Inflammatory Lung Injury via κ Receptors

Butorphanol Promotes Macrophage Phenotypic Transition to Inhibit Inflammatory Lung Injury via κ Receptors

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is characterized by diffuse inflammation of the lung parenchyma and refractory hypoxemia. Butorphanol is commonly used clinically for perioperative pain relief, but whether butorphanol can regulate LPS-induced alveolar macrophage pol...

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Bibliographic Details
Main Authors: Guangxin Luan, Fan Pan, Lina Bu, Kaixuan Wu, Aizhong Wang, Xiaotao Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
butorphanol
acute lung injury
inflammation
macrophage
κ receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.692286/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.692286/full

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