The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response.

Necrotizing enterocolitis (NEC) is a devastating neonatal intestinal inflammatory disease, occurring primarily in premature infants, causing significant morbidity and mortality. The pathogenesis of NEC is associated with an excessive inflammatory IL-8 response. In this study, we hypothesized that th...

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Bibliographic Details
Main Authors: Nanda Nanthakumar, Di Meng, Allan M Goldstein, Weishu Zhu, Lei Lu, Ricardo Uauy, Adolfo Llanos, Erika C Claud, W Allan Walker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21445298/?tool=EBI