In vivo Activity of Copper(II), Manganese(II), and Silver(I) 1,10-Phenanthroline Chelates Against Candida haemulonii Using the Galleria mellonella Model

In vivo Activity of Copper(II), Manganese(II), and Silver(I) 1,10-Phenanthroline Chelates Against Candida haemulonii Using the Galleria mellonella Model

Candida haemulonii is an emerging opportunistic pathogen resistant to most antifungal drugs currently used in clinical arena. Metal complexes containing 1,10-phenanthroline (phen) chelating ligands have well-established anti-Candida activity against different medically relevant species. This study u...

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Bibliographic Details
Main Authors: Rafael M. Gandra, Pauraic McCarron, Livia Viganor, Mariana Farias Fernandes, Kevin Kavanagh, Malachy McCann, Marta H. Branquinha, André L. S. Santos, Orla Howe, Michael Devereux
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
Candida haemulonii
metal-1
10-phenanthroline chelates
Galleria mellonella
antifungal activity
immunomodulation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00470/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00470/full

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