CD3+ Macrophages Deliver Proinflammatory Cytokines by a CD3- and Transmembrane TNF-Dependent Pathway and Are Increased at the BCG-Infection Site

CD3+ Macrophages Deliver Proinflammatory Cytokines by a CD3- and Transmembrane TNF-Dependent Pathway and Are Increased at the BCG-Infection Site

Macrophages are essential cells of the innate immune response against microbial infections, and they have the ability to adapt under both pro- and anti-inflammatory conditions and develop different functions. A growing body of evidence regarding a novel macrophage subpopulation that expresses CD3 ha...

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Bibliographic Details
Main Authors: Adriana Rodriguez-Cruz, Dominique Vesin, Lucero Ramon-Luing, Joaquin Zuñiga, Valérie F. J. Quesniaux, Bernhard Ryffel, Ricardo Lascurain, Irene Garcia, Leslie Chávez-Galán
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
macrophage
CD3
TNF pathway
pro-inflammatory cytokines
BCG infection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02550/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02550/full

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