Relative roles of ABCG5/ABCG8 in liver and intestine[S]

Relative roles of ABCG5/ABCG8 in liver and intestine[S]

ABCG5 (G5) and ABCG8 (G8) form a sterol transporter that acts in liver and intestine to prevent accumulation of dietary sterols. Mutations in either G5 or G8 cause sitosterolemia, a recessive disorder characterized by sterol accumulation and premature coronary atherosclerosis. Hepatic G5G8 mediates...

Full description

Bibliographic Details
Main Authors: Jin Wang, Matthew A. Mitsche, Dieter Lütjohann, Jonathan C. Cohen, Xiao-Song Xie, Helen H. Hobbs
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Journal of Lipid Research
Subjects:
cholesterol/absorption
bile
sterols
transport
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520356170

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520356170

Similar Items