Curcumin analogue C66 attenuates obesity-induced myocardial injury by inhibiting JNK-mediated inflammation

Curcumin analogue C66 attenuates obesity-induced myocardial injury by inhibiting JNK-mediated inflammation

Obesity has been recognized as a major risk factor for the development of chronic cardiomyopathy, which is associated with increased cardiac inflammation, fibrosis, and apoptosis. We previously developed an anti-inflammatory compound C66, which prevented inflammatory diabetic complications via targe...

Full description

Bibliographic Details
Main Authors: Lin Ye, Xiaojun Chen, Minxiu Wang, Leiming Jin, Zaishou Zhuang, Daona Yang, Xinfu Guan, Aleksandr V. Samorodov, Valentin N. Pavlov, Nipon Chattipakorn, Jianpeng Feng, Yi Wang, Wu Luo, Guang Liang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Curcumin derivative
C66
Obesity-related cardiomyopathy
Inflammation
JNK
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221009057

Internet

http://www.sciencedirect.com/science/article/pii/S0753332221009057

Similar Items