Intervertebral disc and endplate cell characterisation highlights annulus fibrosus cells as the most promising for tissue-specific disc degeneration therapy

Degenerative processes of the intervertebral disc (IVD) and cartilaginous endplate lead to chronic spine pathologies. Several studies speculated on the intrinsic regenerative capacity of degenerated IVD related to the presence of local mesenchymal progenitors. However, a complete characterisation of...

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Bibliographic Details
Main Authors: P De Luca, M Castagnetta, L de Girolamo, S Coco, M Malacarne, E Ragni, M Viganò, G Lugano, M Brayda-Bruno, D Coviello, A Colombini
Format: Article
Language:English
Published: AO Research Institute Davos 2020-03-01
Series:European Cells & Materials
Subjects:
Online Access:https://www.ecmjournal.org/papers/vol039/pdf/v039a10.pdf