Significantly Improved Recovery of Recombinant Sonchus Yellow Net Rhabdovirus by Expressing the Negative-Strand Genomic RNA

Generation of recombinant negative-stranded RNA viruses (NSVs) from plasmids involves in vivo reconstitution of biologically active nucleocapsids and faces a unique antisense problem where the negative-sense viral genomic RNAs can hybridize to viral messenger RNAs. To overcome this problem, a positi...

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Bibliographic Details
Main Authors: Xiaonan Ma, Zhenghe Li
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/12/1459