An Enzymatic Flow-Based Preparative Route to Vidarabine

An Enzymatic Flow-Based Preparative Route to Vidarabine

The bi-enzymatic synthesis of the antiviral drug vidarabine (arabinosyladenine, ara-A), catalyzed by uridine phosphorylase from <i>Clostridium perfringens</i> (<i>Cp</i>UP) and a purine nucleoside phosphorylase from <i>Aeromonas hydrophila</i> (<i>Ah</i&g...

Full description

Bibliographic Details
Main Authors: Lucia Tamborini, Clelia Previtali, Francesca Annunziata, Teodora Bavaro, Marco Terreni, Enrica Calleri, Francesca Rinaldi, Andrea Pinto, Giovanna Speranza, Daniela Ubiali, Paola Conti
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
flow bioreactor
enzyme immobilization
nucleoside phosphorylase
vidarabine
nucleosides
Online Access:https://www.mdpi.com/1420-3049/25/5/1223

Internet

https://www.mdpi.com/1420-3049/25/5/1223

Similar Items