Heat shock protein 70 inhibits the activity of Influenza A virus ribonucleoprotein and blocks the replication of virus in vitro and in vivo.

BACKGROUND: Heat shock protein 70 (Hsp70) was identified as a cellular interaction partner of the influenza virus ribonucleoprotein (RNP) complex. The biological significance of the interaction between Hsp70 and RNP has not been fully investigated. PRINCIPAL FINDINGS: Here we demonstrated that Hsp70...

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Bibliographic Details
Main Authors: Gang Li, Junjie Zhang, Xiaomei Tong, Wenjun Liu, Xin Ye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3044721?pdf=render