ELIHKSIR Web Server: Evolutionary Links Inferred for Histidine Kinase Sensors Interacting with Response Regulators

ELIHKSIR Web Server: Evolutionary Links Inferred for Histidine Kinase Sensors Interacting with Response Regulators

Two-component systems (TCS) are signaling machinery that consist of a histidine kinases (HK) and response regulator (RR). When an environmental change is detected, the HK phosphorylates its cognate response regulator (RR). While cognate interactions were considered orthogonal, experimental evidence...

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Bibliographic Details
Main Authors: Claude Sinner, Cheyenne Ziegler, Yun Ho Jung, Xianli Jiang, Faruck Morcos
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Entropy
Subjects:
statistical inference
mutational phenotypes
interaction specificity
phosphorylation
fitness landscape
bacterial signaling
Online Access:https://www.mdpi.com/1099-4300/23/2/170

Internet

https://www.mdpi.com/1099-4300/23/2/170

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