Mitochondrial Complex I Is a Global Regulator of Secondary Metabolism, Virulence and Azole Sensitivity in Fungi.

Mitochondrial Complex I Is a Global Regulator of Secondary Metabolism, Virulence and Azole Sensitivity in Fungi.

Recent estimates of the global burden of fungal disease suggest that that their incidence has been drastically underestimated and that mortality may rival that of malaria or tuberculosis. Azoles are the principal class of antifungal drug and the only available oral treatment for fungal disease. Rece...

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Bibliographic Details
Main Authors: Mike Bromley, Anna Johns, Emma Davies, Marcin Fraczek, Jane Mabey Gilsenan, Natalya Kurbatova, Maria Keays, Misha Kapushesky, Marta Gut, Ivo Gut, David W Denning, Paul Bowyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4954691?pdf=render

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http://europepmc.org/articles/PMC4954691?pdf=render

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