Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display.

Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display.

The C-terminal peptides of ubiquitin (UB) and UB-like proteins (UBLs) play a key role in their recognition by the specific activating enzymes (E1s) to launch their transfer through the respective enzymatic cascades thus modifying cellular proteins. UB and Nedd8, a UBL regulating the activity of cull...

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Bibliographic Details
Main Authors: Bo Zhao, Keya Zhang, Karan Bhuripanyo, Chan Hee J Choi, Eric B Villhauer, Heng Li, Ning Zheng, Hiroaki Kiyokawa, Hermann Schindelin, Jun Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3731359?pdf=render

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http://europepmc.org/articles/PMC3731359?pdf=render

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