Comparative Study of Senescent Th Biomarkers in Healthy Donors and Early Arthritis Patients. Analysis of VPAC Receptors and Their Influence

Comparative Study of Senescent Th Biomarkers in Healthy Donors and Early Arthritis Patients. Analysis of VPAC Receptors and Their Influence

Pro-inflammatory CD4<sup>+</sup>CD28<sup>−</sup> T cells are characteristic of immunosenescence, but also of several autoimmune/inflammatory diseases. Vasoactive intestinal peptide (VIP) acts as an anti-inflammatory and immunomodulatory mediator on these cells. Our objective...

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Bibliographic Details
Main Authors: Raúl Villanueva-Romero, Amalia Lamana, Marissa Flores-Santamaría, Mar Carrión, Selene Pérez-García, Ana Triguero-Martínez, Eva Tomero, Gabriel Criado, José L. Pablos, Isidoro González-Álvaro, Carmen Martínez, Yasmina Juarranz, Rosa P. Gomariz, Irene Gutiérrez-Cañas
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
senescent Th cells
CD4<sup>+</sup>CD28<sup>−</sup> T cells
VPAC receptors
VIP
early arthritis
rheumatoid arthritis
Online Access:https://www.mdpi.com/2073-4409/9/12/2592

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https://www.mdpi.com/2073-4409/9/12/2592

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