Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome

Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome

Urothelial bladder cancer (UBC) are classified into luminal and basal subtypes showing distinct molecular features and clinical behaviour. Recent in silico data have proposed the activation on the Signal Transducer and Activator of Transcription 3 (STAT3) as relevant transcription factor in UBC. To...

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Bibliographic Details
Main Authors: Luisa Benerini Gatta, Laura Melocchi, Mattia Bugatti, Francesco Missale, Silvia Lonardi, Benedetta Zanetti, Luca Cristinelli, Sandra Belotti, Claudio Simeone, Roberto Ronca, Elisabetta Grillo, Sara Licini, Debora Bresciani, Regina Tardanico, Szeman Ruby Chan, Emanuele Giurisato, Stefano Calza, William Vermi
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
STAT3
JAK
basal-type
bladder cancer
MYC
FOSL1
Online Access:https://www.mdpi.com/2072-6694/11/9/1219

Internet

https://www.mdpi.com/2072-6694/11/9/1219

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