Apnea produces neuronal degeneration in the pons and medulla of guinea pigs

Obstructive sleep apnea and other sleep-related breathing disorders result in recurrent periods of oxygen deprivation (hypoxia), hypercapnia and an increase in the cellular production of reactive oxygen species (oxidative stress-related injury). Individuals with these disorders suffer from a variety...

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Bibliographic Details
Main Authors: Jian-Hua Zhang, Simon J. Fung, Mingchu Xi, Sharon Sampogna, Michael H. Chase
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110001944