Evolution of linkage and genome expansion in protocells: The origin of chromosomes.

Chromosomes are likely to have assembled from unlinked genes in early evolution. Genetic linkage reduces the assortment load and intragenomic conflict in reproducing protocell models to the extent that chromosomes can go to fixation even if chromosomes suffer from a replicative disadvantage, relativ...

Full description

Bibliographic Details
Main Authors: András Szilágyi, Viktor Péter Kovács, Eörs Szathmáry, Mauro Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009155