miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression.

miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression.

<h4>Background</h4>In humans and mice naturally occurring CD4(+)CD25(+) regulatory T cells (nTregs) are a thymus-derived subset of T cells, crucial for the maintenance of peripheral tolerance by controlling not only potentially autoreactive T cells but virtually all cells of the adaptive...

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Main Authors: Heiko F Stahl, Tanja Fauti, Nina Ullrich, Tobias Bopp, Jan Kubach, Werner Rust, Paul Labhart, Vassili Alexiadis, Christian Becker, Mathias Hafner, Andreas Weith, Martin C Lenter, Helmut Jonuleit, Edgar Schmitt, Detlev Mennerich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19777054/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19777054/?tool=EBI

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