Typhonium giganteum Lectin Exerts A Pro-Inflammatory Effect on RAW 264.7 via ROS and The NF-κB Signaling Pathway

Typhonium giganteum Lectin Exerts A Pro-Inflammatory Effect on RAW 264.7 via ROS and The NF-κB Signaling Pathway

Typhonii rhizoma, a widely used herb in traditional Chinese medicine, has acute irritating toxicity related to Typhonium giganteum lectin (TGL). TGL exhibits acute inflammatory effects, but the underlying molecular mechanisms are largely unknown. This paper is designed to assess the pro-inflammatory...

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Bibliographic Details
Main Authors: Wei Wang, Hao Wu, Hongli Yu, Xingde Zhang, Guojing Cui, Kuilong Wang, Shanhu Mao, Yaozong Pan
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Toxins
Subjects:
Typhonium giganteum lectin
inflammation
oxidative stress
ROS
NF-κB
apoptosis
necrosis
Bai Fu Zi
Online Access:https://www.mdpi.com/2072-6651/9/9/275

Internet

https://www.mdpi.com/2072-6651/9/9/275

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