Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells.

Plant species from Annonaceae are commonly used in traditional medicine to treat various cancer types. This study aimed to investigate the antiproliferative potential of an alkaloid and acetogenin-rich fraction from the fruit peel of Annona crassiflora in HepG2 cells. A liquid-liquid fractionation w...

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Bibliographic Details
Main Authors: Allisson B Justino, Rodrigo M Florentino, Andressa França, Antonio C M L Filho, Rodrigo R Franco, André L Saraiva, Matheus C Fonseca, Maria F Leite, Foued Salmen Espindola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0250394