Association of Schistosoma mansoni-specific IgG and IgE antibody production and clinical schistosomiasis status in a rural area of Minas Gerais, Brazil.

BACKGROUND: Studies in murine models and human populations have indicated that the collagen-rich granulomatous response against parasite eggs trapped in the liver is associated with the development of severe hepatosplenic schistosomiasis, characterized by periportal fibrosis and portal hypertension....

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Bibliographic Details
Main Authors: Deborah Negrão-Corrêa, Juliana F Fittipaldi, José Roberto Lambertucci, Mauro Martins Teixeira, Carlos Maurício de Figueiredo Antunes, Mariângela Carneiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913716?pdf=render