Berberine Prolongs Mouse Heart Allograft Survival by Activating T Cell Apoptosis via the Mitochondrial Pathway

Berberine Prolongs Mouse Heart Allograft Survival by Activating T Cell Apoptosis via the Mitochondrial Pathway

Berberine, which is a traditional Chinese medicine can inhibit tumorigenesis by inducing tumor cell apoptosis. However, the immunoregulatory of effects berberine on T cells remains poorly understood. Here, we first examined whether berberine can prolong allograft survival by regulating the recruitme...

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Bibliographic Details
Main Authors: Yunhan Ma, Guoliang Yan, Junjun Guo, Fujun Li, Haiping Zheng, Chenxi Wang, Yingyu Chen, Yuhan Ye, Helong Dai, Zhongquan Qi, Guohong Zhuang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
alloimmunity and transplantation
transplantation immunology
immunoregulation
immunological tolerance and memory
T cell
berberine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.616074/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.616074/full

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