Cerebellar granule cells transplanted in vivo can follow physiological and unusual migratory routes to integrate into the recipient cortex

Cerebellar granule cells transplanted in vivo can follow physiological and unusual migratory routes to integrate into the recipient cortex

CNS repair by cell transplantation requires new neurons to integrate into complex recipient networks. We assessed how the migratory route of transplanted granule neurons and the developmental stage of the host rat cerebellum influence engraftment. In both embryonic and postnatal hosts, granule cells...

Full description

Bibliographic Details
Main Authors: Ian Martin Williams, Barbara Carletti, Ketty Leto, Lorenzo Magrassi, Ferdinando Rossi
Format: Article
Language:English
Published: Elsevier 2008-04-01
Series:Neurobiology of Disease
Subjects:
Neural transplantation
Cell replacement
Differentiation
Neuronal migration
Granule cell
Neural progenitors
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000041

Internet

http://www.sciencedirect.com/science/article/pii/S0969996108000041

Similar Items