Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania

Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania

Abstract Background Globally, the majority of people living with HIV have no or only limited access to HIV drug resistance testing to guide the selection of antiretroviral drugs. This is of particular concern for children and adolescents, who experience high rates of treatment failure. The GIVE MOVE...

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Bibliographic Details
Main Authors: Jennifer Anne Brown, Isaac Ringera, Ezekiel Luoga, Molisana Cheleboi, Namvua Kimera, Josephine Muhairwe, Buntshi Paulin Kayembe, Mosa Molapo Hlasoa, Lorraine Kabundi, Ching Wey David Yav, Buoang Mothobi, Lineo Thahane, Alain Amstutz, Nadine Bachmann, Getrud Joseph Mollel, Moniek Bresser, Tracy Renée Glass, Daniel Henry Paris, Thomas Klimkait, Maja Weisser, Niklaus Daniel Labhardt
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Infectious Diseases
Subjects:
HIV
Genotypic resistance testing
Drug resistance
Randomised clinical trial
Antiretroviral therapy
Treatment failure
Online Access:http://link.springer.com/article/10.1186/s12879-020-05491-9

Internet

http://link.springer.com/article/10.1186/s12879-020-05491-9

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