Generation and characterization of human heme oxygenase-1 transgenic pigs.

Xenotransplantation using transgenic pigs as an organ source is a promising strategy to overcome shortage of human organ for transplantation. Various genetic modifications have been tried to ameliorate xenograft rejection. In the present study we assessed effect of transgenic expression of human hem...

Full description

Bibliographic Details
Main Authors: Hye-Jung Yeom, Ok Jae Koo, Jaeseok Yang, Bumrae Cho, Jong-Ik Hwang, Sol Ji Park, Sunghoon Hurh, Hwajung Kim, Eun Mi Lee, Han Ro, Jung Taek Kang, Su Jin Kim, Jae-Kyung Won, Philip J O'Connell, Hyunil Kim, Charles D Surh, Byeong-Chun Lee, Curie Ahn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3465346?pdf=render