Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways

Nitrogen-starved fission yeast cells survive for weeks without dividing. Here, the authors show that some of these surviving cells accumulate mutations in the stress- and mitogen-activated protein kinase pathways and outcompete their parental cells, which provide nutrients for the mutant cells.

Bibliographic Details
Main Authors: Rostyslav Makarenko, Claire Denis, Stefania Francesconi, Serge Gangloff, Benoît Arcangioli
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15880-y